"acute appendicitis"
"the acute phase of the illness"
"acute patients"
"acute pain"
"felt acute annoyance"
"intense itching and burning"
"an acute observer of politics and politicians"
"incisive comments"
"icy knifelike reasoning"
"as sharp and incisive as the stroke of a fang"
"penetrating insight"
"frequent penetrative observations"
"an acute (or critical) lack of research funds"