Corticotropin stimulates the adrenal cortexes to secrete the glucocorticoid hormone cortisol. 促肾上腺皮质激素兴奋肾上腺皮质分泌糖皮质激素考的松。
When glucocorticoid binds to its receptor in the hippocampus, that activates the expression of genes which dampen further synthesis of the hormone. 但过多的糖皮质激素是有害的,所以就有一个停止这种激素分泌的途径。