a serious (sometimes fatal) infection of rodents caused by Yersinia pestis and accidentally transmitted to humans by the bite of a flea that has bitten an infected animal
any epidemic disease with a high death rate
a swarm of insects that attack plants;
"a plague of grasshoppers"
any large scale calamity (especially when thought to be sent by God)
an annoyance;
"those children are a damn plague"
Verb:
cause to suffer a blight;
"Too much rain may blight the garden with mold"
annoy continually or chronically;
"He is known to harry his staff when he is overworked" "This man harasses his female co-workers"